Diabetes Canada is pleased to facilitate an opportunity for Diabetes Canada members and external agencies to post information on clinical trials and solicit participants or partners in a clinical trial study. Clinical Trial is a study or research into the effectiveness and safety profile of a new drug or natural treatment involving both healthy and patient volunteers.. ClinicalTrials.gov This research study is being done to develop educational materials that will help patients and clinicians talk about diabetes treatment and management options. While the potential clinical uses of pulsed electromagnetic field therapy (PEMF) are extensive, we are focusing on the potential benefits of PEMF on vascular health. The purpose of this trial is to test if VC-01™ combination product can be implanted subcutaneously in subjects with Type 1 Diabetes and maintained safely for two years. Two New Clinical Trials (HCQ and Baby Teeth Stem Cells) Hydroxychloroquine to Prevent Type 1 Diabetes . There has been a 50 per cent increase in clinical trials in Adelaide as a result of the state’s safe-haven status throughout the COVID-19 pandemic, the general manager of … The GRADE Study is a pragmatic, unmasked clinical trial that will compare commonly used diabetes medications, when combined with metformin, on glycemia-lowering effectiveness and patient-centered outcomes. Patients with Type 2 Diabetes aged 18-65 are needed for a paid clinical trial testing a new drug which may be useful in the treatment of Type 2 Diabetes Mellitus. The purpose of this study is to assess the effectiveness of a digital storytelling intervention derived through a community based participatory research (CBPR) approach on self-management of type 2 diabetes (T2D) among Somali adults. What are the findings so far? The goal of this study is to understand how and why insulin resistant individuals respond differently to exercise as compared with insulin sensitive individuals at the skeletal muscle and gene expression level. This clinical trial will identify exercise-related and emotional stress related effects on glycemic control in patients with type 1 diabetes using sensor-augmented pump (SAP) therapy. They will be enrolled in the study regardless of their prior diabetes regimen, including using Multiple Daily Injections (MDI), Continuous Subcutaneous Insulin Infusion (CSII) or Sensor-Augmented Pump therapy (SAP). Can QBSAfe be implemented in a clinical practice setting and improve quality of life, reduce treatment burden and hypoglycemia among older, complex patients with type 2 diabetes? The purpose of this study is to gather preliminary data to better understand acute effects of exercise on glucose metabolism. Search for closest city to find more detailed information on a research study in your area. The purpose of this study is to understand nighttime glucose regulation in humans and find if the pattern is different in people with Type 2 diabetes. Type1Screen is a new Australian and New Zealand initiative offering free type 1 diabetes risk screening. Dr. Melton was a prominent scientist and this life-changing event triggered him to begin … Clinical trials are an important step in our being able to have new treatments for diabetes and other conditions. A Pilot Phase involving up to 7 participants using the study system for 10-14 days will be conducted prior to the crossover trial. The purpose of this study is to assess whether psyllium is more effective in lowering fasting blood sugar and HbA1c, and to evaluate the effect of psyllium compared to wheat dextrin on the following laboratory markers:  LDL-C, inflammatory markers such as ceramides and hsCRP, and branch chain amino acids which predict Diabetes Mellitus (DM). Diabetes Clinical Trials. The study is designed to understand the confidence and competence level of patients with type 1 diabetes mellitus in their ability to make changes to their insulin pump. The purpose of this study is to evaluate the safety and efficacy of oral Pyridorin 300 mg BID in reducing the rate of progression of nephropathy due to type 2 diabetes mellitus. Currently, there are more than 70 JDRF-funded clinical trials, to both prevent and treat this disease and its complications. The purpose of this study is to identify immune mediated diabetes in patients treated with PD 1 inhibitors, and characterizing its clinical course, laboratory features and possible risk factors. Researchers will start a new human clinical trial of a new type 1 diabetes treatment that could cure the disease and stop the need for painful insulin injections. The objective for thisstudy is to characterize the impact of glycemic excursions on cognition in Type 1 Diabetes (T1D) and determine mediators and moderators of this relationship. The purpose of this study is to demonstrate that a morning injection of Toujeo compared to Lantus will provide better glycemic control, as shown  by Continuous Glucose Monitoring (CGM), in adult patients with type 1 diabetes mellitus. An Israeli company claiming to have created a tiny micro-pancreas that can “cure” diabetes for millions of people has said it will submit a request next month for human clinical trials in the UK. To determine if the EndoBarrier safely and effectively improves glycemic control in obese subjects with type 2 diabetes. American Diabetes Association®. The drug, semaglutide, made by Novo Nordisk, already is marketed as a treatment for Type 2 diabetes. Type 1 Diabetes TrialNet is an international network of researchers who are exploring ways to prevent, delay and reverse the progression of type 1 diabetes. The purpose of this study is to collect device data to assist in the development of a Personalized Closed Loop (PCL) system. The purpose of this study is to prospectively assemble a cohort of subjects >50 and ≤85 years of age with New-onset Diabetes (NOD): The purpose of this study is to determine if children with type 1 diabetes have adequate immune response to PPSV23 vaccination and to assess factors affecting immune response. Glucose metabolism will be assessed by labeled oral glucose tolerance test and liver fat by magnetic resonance spectroscopy pre randomization and at 8 and 12 week after starting dietary intervention. We are targeting, the pre diabetic - metabolic syndrome population, a group with high prevalence in the American population. The purpose of this study is to evaluate whether or not semaglutide can slow down the growth and worsening of chronic kidney disease in people with type 2 diabetes. The National Institutes of Health (NIH), a part of the U.S. Department of Health and Human Services, is the nation's medical research agency—making important discoveries that improve health and save lives. The study is being done to find out if low blood sugar (hypoglycemia) can be reduced in people with type 1 diabetes (T1D) 65 years and older with use of automated insulin delivery (AID) system. The Type 1 diabetes Immunotherapy Consortium (T1D UK) brings together researchers from across the UK to run trials that develop and test new immunotherapies. The rationale for this study is as follows: we anticipate that closed-loop control may ultimately be adopted by patients with T1DM in a selective manner. The objective of this study is to evaluate the EWIS in patients with type 1 diabetes on insulin pump therapy. This purpose of this study is to determine if activation of a person's immune system in the small intestine could be a contributing cause of Type 1 Diabetes. The study is being undertaken to understand how a gastric bypass can affect a subject's diabetes even prior to their losing significant amounts of weight. To understand why patients with indigestion with or without diabetes have gastrointestinal symptoms and in particular to understand where the symptoms are related to increased sensitivity to nutrients. We are looking for participants who: are 18 to 85 years old have type 2 diabetes are taking stable diabetes medications for the past 12 weeks. A total of up to 300 subjects will be enrolled at up to 20 investigational centers in the US in order to have 240 subjects meeting eligibility criteria. The device systems used in this study are approved by the Food and Drug Administration (FDA) for diabetes management. However, it is now recognized that a small portion of the population with diabetes have an underlying problem with their pancreas, such as chronic pancreatitis or pancreatic cancer, as the cause of their diabetes. Search. To describe characteristics of families who are likely to participate. The purpose of this study is to assess a novel informatics approach that incorporates the use of patient’s diabetes self-care data into the design and delivery of individualized education interventions to improve diabetes control. 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